Given rapid urbanization across the globe, coping with humans is an important aspect of life for most animals. Although human presence is often accompanied by human associated predators such as dogs, the effects of humans and dogs on animal physiology are rarely considered together. Here, we leverage over 4,500 measures of fecal glucocorticoid metabolites (FGMs), a biomarker of physiological “stress”, collected from California ground squirrels (Otospermophilus beecheyi) from two sites differing in human activity. Drawing from twelve years of study, we explored the effects of dispersal status, human presence, and dog activity on FGMs in adults and juveniles. Between-site dispersal revealed site-level effects on stress physiology. Whereas FGMs increased after immigrants moved to the more disturbed site, those dispersing to the less disturbed site failed to subsequently reduce FGMs. Responses to human and dog activity were age- and mass- dependent. Whereas juvenile FGMs did not covary with dog activity, juveniles trapped in areas with high human activity had elevated FGMs. In contrast, dogs represented a major stressor for adult animals, but the effects were generally shielded by human presence. These findings uncover complex relationships among anthropogenic factors, stress physiology, and habitat selection in wild animals living in a human-influenced world.
