Tumor ablation is an effective treatment for cancer removal, but current methods can be improved using biocompatible materials to minimize complications and post-operative pain. The procedure uses a needle-like probe to burn or freeze cancerous target tissue. An essential component to this procedure is separating healthy tissue from the target tissue to prevent damage. Current methods use saline or carbon dioxide, which cause complications within the body cavity due to gravity. The development of a biocompatible foam through partnership between UW- Eau Claire and Mayo Clinic Health System allows for thermal insulation and maintained contact with the target tissue. FDA approved biocompatible materials are used to create foam that is stable throughout the procedure. Current project goals include continuing characterization of foam properties through rheology, measuring surface tension through pendent drop tensiometry, and developing freeze drying and an automated procedural device for long-term storage and clinical adoption. Quantifying foam properties through these characterization techniques and data collection allows for clinical readiness. Refinement of the biocompatible foam aims to optimize the tumor ablation procedure, resulting in minimized complications and enhanced patient outcomes.