This study investigates the emergence of American users on RedNote (also known as Xiaohongshu), examining how this shift fosters intercultural communication between American and Chinese netizens. Through an interdisciplinary approach and qualitative analysis of posts and bilingual discussions under the TikTok Refugee, this research explores themes of cultural exchange, language adaptation, and the risks of digital miscommunication. Findings will provide insights into the evolving dynamics of global social media interaction and its implications for intercultural education and communication.